Vantrela ER

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Vantrela ER is a strong opioid pain medication used to manage pain severe enough to require daily, around-the-clock, long-term treatment with an opioid. Never give anyone else this medication.

Vantrela ER Overview

Reviewed: March 29, 2017
Updated: 

Vantrela ER is a prescription medication used to relieve severe pain in adults who require around-the-clock, long-term treatment.

Vantrela ER belongs to a group of drugs called narcotic analgesics. These drugs work by changing the way that the brain and nervous system respond to pain.

This medication comes in extended-release tablet form and is taken twice a day with a full glass of water.

Do not chew, divide, crush, dissolve, or break Vantrela ER tablets. Swallow the tablets whole.

Common side effects include nausea, constipation, and headache. Vantrela ER can make you dizzy or sleepy. Do not drive or operate heavy machinery until you know how it affects you.

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  • Lung Diseases, Obstructive
  • Pain, Postoperative

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Vantrela ER FDA Warning

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WARNING:

  • ADDICTION, ABUSE, AND MISUSE 
  • LIFE-THREATENING RESPIRATORY DEPRESSION
  • ACCIDENTAL INGESTION
  • NEONATAL OPIOID WITHDRAWAL SYNDROME
  • CYTOCHROME P450 3A4 INTERACTION
  • RISKS FROM CONCOMITANT USE WITH BENZODIAZEPINES OR OTHER CNS DEPRESSANTS

  •  Vantrela ER exposes users to risks of addiction, abuse, and misuse which can lead to overdose and death. 

  • Serious, life-threatening, or fatal respiratory depression may occur. 

  • Accidental ingestion of Vantrela ER, especially by children, can result in a fatal overdose from Vantrela ER.

  • Prolonged use of Vantrela ER during pregnancy can result in neonatal opioid withdrawal syndrome, which may be life-threatening if not recognized and treated.

  • Co-administration with CYP3A4 inhibitors (or discontinuation of CYP3A4 inducers) can result in a fatal overdose from Vantrela ER. 

  • Co-administration of opioids with benzodiazepines or other central nervous system (CNS) depressants, including alcohol, may result in profound sedation, respiratory depression, coma, and death.