Turalio

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Turalio is used to treat tenosynovial giant cell tumor (TGCT) that is not likely to improve with surgery. Turalio can cause serious liver problems.

Turalio Overview

Reviewed: September 8, 2019
Updated: 

Turalio is a prescription medication used to treat adults with tenosynovial giant cell tumor (TGCT) that is not likely to improve with surgery.

Turalio belongs to a group of drugs called kinase inhibitors. In tenosynovial giant cell tumor (TGCT), a small number of cells that line the joints can have a defect that causes them to make too much of a protein called colony-stimulating factor 1 (CSF-1). CSF-1 acts like a magnet and attracts inflammatory cells into the joint space to form a tumor. Turalio blocks the signals of CSF-1.

This medication comes in capsule form. It is taken twice daily on an empty stomach, at least 1 hour before or 2 hours after a meal or snack. Swallow Turalio capsules whole. Do not open, break, or chew the capsules.

Common side effects include changes in blood liver tests, hair color changes and tiredness.

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Turalio Drug Class

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Turalio is part of the drug class:

Turalio FDA Warning

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WARNING: HEPATOTOXICITY

  • TURALIO can cause serious and potentially fatal liver injury.

  • Monitor liver tests prior to initiation of TURALIO and at specified intervals during treatment. Withhold and dose reduce or permanently discontinue TURALIO based on severity of hepatotoxicity.

  • TURALIO is available only through a restricted program called the TURALIO Risk Evaluation and Mitigation Strategy (REMS) Program.