Trikafta

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Trikafta is used to treat cystic fibrosis (CF). Take Trikafta with food that contains fat.

Trikafta Overview

Reviewed: April 14, 2020
Updated: 

Trikafta is a prescription medication used to treat cystic fibrosis (CF) in people aged 12 years and older who have at least one copy of the F508del mutation in the cystic fibrosis transmembrane conductance regulator (CFTR) gene. Trikafta contains 3 medicines elexacaftor, tezacaftor and ivacaftor.

Trikafta belongs to a group of drugs called CFTR modulators. They work by correcting the malfunctioning CFTR gene to restore normal activity.

Trikafta comes as two different tablets. Take 2 orange tablets in the morning. Take 1 light blue tablet in the evening. Always take Trikafta with food that contains fat.

Common side effects include headache, diarrhea and upper respiratory infections. Trikafta may cause dizziness. Do not drive a car or operate heavy machinery until you know how this medication affects you.

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Trikafta Drug Class

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Trikafta is part of the drug class: