Siliq

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Siliq treats a skin condition called plaque psoriasis. It may lower the ability of your immune system to fight infections. Tell your doctor if you have signs and symptoms of infection such as a fever.

Siliq Overview

Reviewed: July 12, 2017
Updated: 

Siliq is a prescription medication used to treat adults with moderate to severe plaque psoriasis (a skin condition in which red patches with silvery scales form on some areas of the body).

Siliq belongs a class of medications called monoclonal antibodies. It works by blocking the action of a certain natural substance in the body that causes the symptoms of psoriasis.

This medication is available in an injectable form to be given just under the skin (subcutaneously). 

Common side effects of Siliq include joint pain, headache, and tiredness.

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Siliq FDA Warning

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Warning: suicidal ideation and behavior

Suicidal thoughts or behavior have happened in some people treated with Siliq. Some people have ended their own lives. Your risk of suicidal thoughts and behavior may be increased if you have a history of suicidal thoughts or depression. Tell your doctor immediately if you notice any signs of suicidal thoughts or behavior, new onset or worsening depression, anxiety, or other mood changes. Your healthcare professional might refer you to a mental health professional, as appropriate. 

Because of the observed suicidal behavior in subjects treated with Siliq, Siliq is available only through a restricted program under a Risk Evaluation and Mitigation Strategy (REMS) called the Siliq REMS Program.

Your healthcare provider will give you a Siliq Patient Wallet Card about symptoms you should get medical help for right away. Carry the card with you at all times during treatment with Siliq and show it to all of your healthcare providers.