Myrbetriq

Myrbetriq is a prescription medication used to treat overactive bladder. Myrbetriq belongs to a group of drugs called beta-3 adrenergic agonists, which help the bladder muscles to relax.

This medication comes in tablet form and is taken once a day, with water. Myrbetriq can be taken with or without food.

Common side effects include increased blood pressure, cold symptoms, and headache.

Myrbetriq is a prescription medication used to treat adults with the symptoms of overactive bladder.

Symptoms of overactive bladder include:

• urinary frequency (urinating often)
• urinary urgency (a strong need to urinate right away)
• urinary incontinence (leakage)

This medication may be prescribed for other uses. Ask your doctor or pharmacist for more information.

• Astellas Pharma US, Inc.

Myrbetriq may cause serious side effects including:

• increased blood pressure. Myrbetriq may cause your blood pressure to increase or make your blood pressure worse if you have a history of high blood pressure. It is recommended that your doctor check your blood pressure while you are taking Myrbetriq.
• inability to empty your bladder (urinary retention). Myrbetriq may increase your chances of not being able to empty your bladder if you have bladder outlet obstruction or if you are taking other medicines to treat overactive bladder. Tell your doctor right away if you are unable to empty your bladder.

The most common side effects of Myrbetriq include:

• increased blood pressure
• common cold symptoms (nasopharyngitis)
• urinary tract infection
• headache

Tell your doctor if you have any side effect that bothers you or that does not go away or if you have hives, skin rash or itching while taking Myrbetriq.

These are not all the possible side effects of Myrbetriq. For more information, ask your doctor or pharmacist.

Tell your doctor about all the medicines you take, including prescription and non-prescription medicines, vitamins, and herbal supplements. Myrbetriq may affect the way other medicines work, and other medicines may affect how Myrbetriq works.

Tell your doctor if you take:

• thioridazine (Mellaril or Mellaril-S)
• flecainide (Tambocor)
• propafenone (Rythmol)
• digoxin (Lanoxin)

This is not a complete list of Myrbetriq drug interactions. Ask your doctor or pharmacist for more information.

Do not take Myrbetriq if you are allergic to it. 

Myrbetriq can increase blood pressure. Your doctor should check your blood pressure often while you are taking Myrbetriq, particularly if you have a history of high blood pressure. 

This medication has caused urinary retention in patients with bladder outlet obstruction (BOO) and in patients taking antimuscarinic medicines for overactive bladder. Talk to your doctor if you are unsure if this applies to you. 

Medicines can interact with certain foods. In some cases, this may be harmful and your doctor may advise you to avoid certain foods. In the case of Myrbetriq there are no specific foods that you must exclude from your diet when receiving this medication.

Before you take Myrbetriq, tell your doctor if you:

• have liver problems
• have kidney problems
• have very high uncontrolled blood pressure
• have trouble emptying your bladder or you have a weak urine stream
• are pregnant or plan to become pregnant. It is not known if Myrbetriq will harm your unborn baby. Talk to your doctor if you are pregnant or plan to become pregnant.
• are breastfeeding or plan to breastfeed. It is not known if Myrbetriq passes into your breast milk. You and your doctor should decide if you will take Myrbetriq or breastfeed. You should not do both.

Tell your doctor about all the medicines you take, including prescription and nonprescription medicines, vitamins, and herbal supplements. 

Tell your doctor if you are pregnant or plan to become pregnant.

The FDA categorizes medications based on safety for use during pregnancy. Five categories - A, B, C, D, and X, are used to classify the possible risks to an unborn baby when a medication is taken during pregnancy.

Myrbetriq falls into category C. In animal studies, pregnant animals were given this medication and had some babies born with problems. No well-controlled studies have been done in humans. Therefore, this medication may be used if the potential benefits to the mother outweigh the potential risks to the unborn child.

Tell your doctor if you are breastfeeding or plan to breastfeed. No studies have been conducted to assess the impact of Myrbetriq on milk production in humans, its presence in human breast milk, or its effects on the breast-fed child. Because Myrbetriq is predicted to be excreted in human milk and because of the potential for serious adverse reactions in nursing infants, talk to your doctor about whether you should discontinue nursing or discontinue taking this medicine.

Take Myrbetriq exactly as your doctor tells you to take it.

• You should take 1 Myrbetriq tablet once a day, with water. Swallow the tablet whole. Never crush or chew it.
• You can take Myrbetriq with or without food.
• If you miss a dose of Myrbetriq , begin taking it again the next day. Do not take 2 doses of Myrbetriq the same day.
• If you take too much Myrbetriq, call your doctor or go to the nearest hospital emergency room right away.

The recommended starting dose of Myrbetriq is 25 mg once daily with or without food. Myrbetriq 25 mg is effective within 8 weeks. The dose may be increased to 50 mg once daily, if needed.

The daily dose of Myrbetriq should not be more than 25 mg once daily in people with severe kidney disease or moderate liver disease.

If you take too much Myrbetriq, call your local Poison Control Center or seek emergency medical attention right away.

• Store Myrbetriq at room temperature, between 59˚F to 86˚F (15˚C to 30˚C). Keep the bottle closed.
• Safely throw away medicine that is out of date or no longer needed.
• Keep Myrbetriq and all medicines out of the reach of children.