Mavyret

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Mavyret is a prescription medication that treats hepatitis C infection. Take Mavyret with food.

Mavyret Overview

Reviewed: October 27, 2017
Updated: 

Mavyret is a prescription medication that is used to treat certain types of chronic (long-term) hepatitis C infection (inflammation of the liver caused by a virus) in adults. 

Mavyret is a single product containing 2 medications: glecaprevir and pibrentasvir. Glecaprevir belongs to a group of drugs called HCV NS3/4A protease inhibitors. They work by decreasing the amount of HCV in the body. Pibrentasvir belongs to a class of medications called HCV NS5A inhibitors. They work by stopping the virus that causes hepatitis C from spreading inside the body.

Mavyret comes in a tablet form and is typically taken once daily with food.

Common side effects of Mavyret include headache and tiredness. Since Mavyret can cause tiredness, do not drive or operate heavy machinery until you know how Mavyret affects you.

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Mavyret Drug Class

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Mavyret is part of the drug class:

Mavyret FDA Warning

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Warning: risk of hepatitis B virus reactivation.

You may already be infected with hepatitis B (a virus that infects the liver and may cause severe liver damage) but not have any symptoms of the disease. In this case, taking Mavyret may increase the risk that your infection will become more serious or life-threatening and you will develop symptoms. Tell your doctor if you have or ever had a hepatitis B virus infection. Your doctor will order a blood test to see if you have or have ever had hepatitis B infection. Your doctor will also monitor you for signs of hepatitis B infection during and for several months after your treatment. If necessary, your doctor may give you medication to treat this infection before and during your treatment with Mavyret. If you experience any of the following symptoms during or after your treatment, call your doctor immediately: excessive tiredness, yellowing of the skin or eyes, loss of appetite, nausea or vomiting, pale (lighter colored) stools, stomach pain (right side of the belly below the ribs), or dark urine.

Keep all appointments with your doctor and the laboratory. Your doctor may order certain tests before, during, and after your treatment to check your body's response to Mavyret.