Mavenclad

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Mavenclad treats relapsing forms of multiple sclerosis (MS). Do not take this medication if you are pregnant or have cancer.

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Mavenclad Overview

Reviewed: April 1, 2019
Updated: 

Mavenclad is a prescription medication used to treat relapsing multiple sclerosis (MS).

Mavenclad belongs to a group of drugs called antimetabolites. It is thought to work by preventing B- and T-cells from replicating in the body, thus reducing the number of these types of cells in circulation.

This medication comes in tablet form and is given as two yearly treatment courses. Each yearly treatment course consists of 2 treatment weeks (also called cycles) that will be about a month apart. Mavenclad tablets are taken with water, and swallowed whole without chewing.

Common side effects of Mavenclad include upper respiratory tract infection, headache, and lymphopenia (low blood cell count).

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  • Other
  • Leukemia, Hairy Cell
  • Leukemia, Lymphocytic, Chronic, B-cell
  • Lymphoma, Non-hodgkin
  • Multiple Sclerosis

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Mavenclad Drug Class

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Mavenclad is part of the drug class:

Mavenclad FDA Warning

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WARNING: MALIGNANCIES AND RISK OF TERATOGENICITY 

 Malignancies Treatment with MAVENCLAD may increase the risk of malignancy. MAVENCLAD is contraindicated in patients with current malignancy. In patients with prior malignancy or with increased risk of malignancy, evaluate the benefits and risks of the use of MAVENCLAD on an individual patient basis. Follow standard cancer screening guidelines in patients treated with MAVENCLAD.

 Risk of Teratogenicity MAVENCLAD is contraindicated for use in pregnant women and in women and men of reproductive potential who do not plan to use effective contraception because of the potential for fetal harm. Malformations and embryolethality occurred in animals. Exclude pregnancy before the start of treatment with MAVENCLAD in females of reproductive potential. Advise females and males of reproductive potential to use effective contraception during MAVENCLAD dosing and for 6 months after the last dose in each treatment course. Stop MAVENCLAD if the patient becomes pregnant.