Durvalumab
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Durvalumab is an infusion used to treat bladder and urinary tract cancer as well as Stage III non-small cell lung cancer. Durvalumab may cause fatigue, muscle/bone pain, and constipation.
Durvalumab Overview
Durvalumab is a prescription injection used to treat certain cases of bladder and urinary tract cancer. It can also be used to treat certain cases of Stage III non-small cell lung cancer. Imfinzi belongs to a group of drugs called monoclonal antibodies. It works by helping your immune system to slow or stop the growth of cancer cells.
Durvalumab is an injectable solution to be given directly into the vein (IV) by a healthcare professional.
Common side effects of durvalumab include fatigue, muscle/bone pain, constipation, and decreased appetite.
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Uses of Durvalumab
Durvalumab is a prescription injection used to treat:
- a type of cancer in the bladder and urinary tract and can be given when:
- cancer has spread or can not be removed with surgery, and
- you have tried chemotherapy that contains platinum, and it did not work or is no longer working
- Stage III non-small cell lung cancer that
- has spread outside the chest
- cannot be removed by surgery, and
- has responded or become stable with initial chemotherapy treatment that contains platinum (given at the same time as radiation)
This medication may be prescribed for other uses. Ask your doctor or pharmacist for more information.
Durvalumab Drug Class
Durvalumab is part of the drug class:
Side Effects of Durvalumab
Serious side effects of durvalumab have been reported. See the "Durvalumab Precautions" section.
Common side effects of durvalumab include
- fatigue
- muscle/bone pain
- constipation
- decreased appetite
- nausea
- swelling of the hands or feet
- urinary tract infection
This is not a complete list of durvalumab side effects. Ask your doctor or pharmacist for more information. Tell your doctor if you have any side effects that bother you or that do not go away. Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.
Durvalumab Food Interactions
Medications can interact with certain foods. In some cases, this may be harmful and your doctor may advise you to avoid certain foods. In the case of durvalumab, there are no specific foods that you must exclude from your diet when receiving this medication.
Inform MD
Before taking durvalumab, tell your doctor about all of your medical conditions. Especially tell them if you:
- are allergic to durvalumab or any of its ingredients
- have ever had an organ transplant
- have an autoimmune disease
- have lung disease
- have a liver disease
- are pregnant or plan to become pregnant
- are breastfeeding or plan to breastfeed
Tell your doctor about all the medicines you take including prescription and non-prescription medicines, vitamins, and herbal supplements.
Durvalumab and Pregnancy
Tell your doctor if you are pregnant or plan to become pregnant.
In animal studies, pregnant animals were given durvalumab, and some babies had problems. There are no well-controlled studies that have been done in pregnant women. Therefore, durvalumab may be used if the potential benefits to the mother outweigh the potential risks to the unborn child.
f you are able to become pregnant, it is recommended you use an effective method of birth control during your treatment and for at least 3 months after the last dose of durvalumab. Talk to your healthcare provider about which birth control methods are the best options for you.
Durvalumab and Lactation
Tell your doctor if you are breastfeeding or plan to breastfeed.
It is not known if durvalumab crosses into the breast milk. Because many medications can cross into human milk and because of the possibility for serious adverse reactions in nursing infants, a choice should be made whether to stop nursing or to stop the use of durvalumab. The importance of the drug to the mother should be considered.
It is recommended you do not breastfeed during treatment and for at least 3 months after the last dose of durvalumab.
Durvalumab Usage
Durvalumab Overdose
Since durvalumab is administered by a healthcare provider in a medical setting, it is unlikely that an overdose will occur. However, if overdose is suspected, seek emergency medical attention.
Other Requirements
Keep all appointments with your doctor and the laboratory. Your doctor will order specific lab testing to check your body's response to Imfinzi.